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Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer.
Goumas, Freya A; Holmer, Reinhild; Egberts, Jan-Hendrik; Gontarewicz, Artur; Heneweer, Carola; Geisen, Ulf; Hauser, Charlotte; Mende, Maria-Margarete; Legler, Karen; Röcken, Christoph; Becker, Thomas; Waetzig, Georg H; Rose-John, Stefan; Kalthoff, Holger.
Afiliação
  • Goumas FA; Clinic for General Surgery, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Holmer R; Division of Molecular Oncology, Institute for Experimental Cancer Research, CCC-North, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Egberts JH; Clinic for General Surgery, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Gontarewicz A; Institute of Pathology, Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Heneweer C; Clinic for Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Geisen U; Division of Molecular Oncology, Institute for Experimental Cancer Research, CCC-North, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Hauser C; Clinic for General Surgery, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Mende MM; Division of Molecular Oncology, Institute for Experimental Cancer Research, CCC-North, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Legler K; Division of Molecular Oncology, Institute for Experimental Cancer Research, CCC-North, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Röcken C; Institute of Pathology, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Becker T; Clinic for General Surgery, Visceral, Thoracic, Transplantation and Pediatric Surgery, University Hospital Schleswig-Holstein, Kiel, Germany.
  • Waetzig GH; CONARIS Research Institute AG, Kiel, Germany.
  • Rose-John S; Institute of Biochemistry, Christian-Albrechts-University, Kiel, Germany.
  • Kalthoff H; Division of Molecular Oncology, Institute for Experimental Cancer Research, CCC-North, University Hospital Schleswig-Holstein, Kiel, Germany.
Int J Cancer ; 137(5): 1035-46, 2015 Sep 01.
Article em En | MEDLINE | ID: mdl-25604508
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proteínas Recombinantes de Fusão / Interleucina-6 / Carcinoma Ductal Pancreático / Anticorpos Monoclonais Humanizados Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Int J Cancer Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proteínas Recombinantes de Fusão / Interleucina-6 / Carcinoma Ductal Pancreático / Anticorpos Monoclonais Humanizados Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Int J Cancer Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha