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Fumarate induces redox-dependent senescence by modifying glutathione metabolism.
Zheng, Liang; Cardaci, Simone; Jerby, Livnat; MacKenzie, Elaine D; Sciacovelli, Marco; Johnson, T Isaac; Gaude, Edoardo; King, Ayala; Leach, Joshua D G; Edrada-Ebel, RuAngelie; Hedley, Ann; Morrice, Nicholas A; Kalna, Gabriela; Blyth, Karen; Ruppin, Eytan; Frezza, Christian; Gottlieb, Eyal.
Afiliação
  • Zheng L; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
  • Cardaci S; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
  • Jerby L; The Blavatnik School of Computer Science-Tel Aviv University, Tel Aviv 69978, Israel.
  • MacKenzie ED; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
  • Sciacovelli M; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK.
  • Johnson TI; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK.
  • Gaude E; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK.
  • King A; Institute of Cancer Sciences, University of Glasgow, Switchback Road, Glasgow G61 1BD, UK.
  • Leach JD; School of Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Bearsden Road, Glasgow G61 1QH, UK.
  • Edrada-Ebel R; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 16 Richmond Street, Glasgow G1 1XQ, UK.
  • Hedley A; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
  • Morrice NA; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
  • Kalna G; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
  • Blyth K; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
  • Ruppin E; 1] The Blavatnik School of Computer Science-Tel Aviv University, Tel Aviv 69978, Israel [2] The Sackler School of Medicine-Tel Aviv University, Tel Aviv 69978, Israel.
  • Frezza C; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK.
  • Gottlieb E; Cancer Research UK, Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
Nat Commun ; 6: 6001, 2015 Jan 23.
Article em En | MEDLINE | ID: mdl-25613188
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumaratos / Glutationa Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumaratos / Glutationa Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido