Direct arylation of sydnones with aryl chlorides toward highly substituted pyrazoles.
J Org Chem
; 80(4): 2467-72, 2015 Feb 20.
Article
em En
| MEDLINE
| ID: mdl-25635522
ABSTRACT
The direct arylation of the C4 position of both N-alkyl- and N-arylsydnones with aryl/heteroaryl chlorides has been realized. The reaction is quite general and allows access to a wide range of 4-substituted sydnones. Yields of more challenging substrates can be improved through the use of aryl bromides.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pirazóis
/
Sidnonas
/
Hidrocarbonetos Clorados
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Reino Unido