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Isolation and cytotoxicity evaluation of the chemical constituents from Cephalantheropsis gracilis.
Chang, Chi-Fen; Hsu, Yu-Lin; Lee, Chao-Ying; Wu, Chia-Hua; Wu, Yang-Chang; Chuang, Ta-Hsien.
Afiliação
  • Chang CF; Department of Anatomy, School of Medicine, China Medical University, Taichung 40402, Taiwan. cfchang@mail.cmu.edu.tw.
  • Hsu YL; Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan. lynn4051@yahoo.com.tw.
  • Lee CY; School of Pharmacy, China Medical University, Taichung 40402, Taiwan. cylee@mail.cmu.edu.tw.
  • Wu CH; School of Pharmacy, China Medical University, Taichung 40402, Taiwan. u101003312@cmu.edu.tw.
  • Wu YC; School of Pharmacy, China Medical University, Taichung 40402, Taiwan. yachwu@mail.cmu.edu.tw.
  • Chuang TH; Research Center for Chinese Herbal Medicine, China Medical University, Taichung 40402, Taiwan. yachwu@mail.cmu.edu.tw.
Int J Mol Sci ; 16(2): 3980-9, 2015 Feb 12.
Article em En | MEDLINE | ID: mdl-25686035
ABSTRACT
Cephalantheropsis gracilis afforded five new compounds cephalanthrin-A (1), cephalanthrin-B (2), cephathrene-A (3), cephathrene-B (4), methyl 2-(aminocarbonyl) phenylcarbamate (5), and 52 known compounds. The structures of the new compounds were determined by spectroscopic analysis. Among the compounds isolated, tryptanthrin (6), phaitanthrin A (7), cephalinone D (19), and flavanthrin (30) showed significant cytotoxicity against MCF-7, NCI-H460, and SF-268 cell lines.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Orchidaceae / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Orchidaceae / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Taiwan