Methods of glioma sample processing for molecular diagnosis for the glioma tissue bank project.
Biopreserv Biobank
; 13(1): 31-6, 2015 Feb.
Article
em En
| MEDLINE
| ID: mdl-25686045
ABSTRACT
Genome-wide sequencing in glioma samples provides comprehensive insights into oncogenesis and malignant transformation. Several distinct biomarkers have been proven to have clinical significance and are being widely applied in routine clinical practice. Standard sample processing lays the foundation for successful molecular testing. In this study, we found intraoperative neuronavigation ensured higher tumor purity during sample collection, and an automated device helped improve DNA quality and increased yields. These two technologies are beneficial for glioma tissue bank construction and provide for accurate molecular testing during routine clinical practice.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bancos de Tecidos
/
Neoplasias Encefálicas
/
Análise de Sequência de DNA
/
Neuronavegação
/
Glioma
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Biopreserv Biobank
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
China