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Potent and selective Bruton's tyrosine kinase inhibitors: discovery of GDC-0834.
Young, Wendy B; Barbosa, James; Blomgren, Peter; Bremer, Meire C; Crawford, James J; Dambach, Donna; Gallion, Steve; Hymowitz, Sarah G; Kropf, Jeffrey E; Lee, Seung H; Liu, Lichuan; Lubach, Joseph W; Macaluso, Jen; Maciejewski, Pat; Maurer, Brigitte; Mitchell, Scott A; Ortwine, Daniel F; Di Paolo, Julie; Reif, Karin; Scheerens, Heleen; Schmitt, Aaron; Sowell, C Gregory; Wang, Xiaojing; Wong, Harvey; Xiong, Jin-Ming; Xu, Jianjun; Zhao, Zhongdong; Currie, Kevin S.
Afiliação
  • Young WB; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Barbosa J; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Blomgren P; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Bremer MC; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Crawford JJ; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Dambach D; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Gallion S; St. Andrews Circle, Wallingford, CT 06492, United States.
  • Hymowitz SG; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Kropf JE; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Lee SH; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Liu L; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Lubach JW; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Macaluso J; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Maciejewski P; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Maurer B; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Mitchell SA; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Ortwine DF; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Di Paolo J; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Reif K; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Scheerens H; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Schmitt A; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Sowell CG; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Wang X; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Wong H; Genentech, 1 DNA Way, South San Francisco, CA 94080, United States.
  • Xiong JM; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Xu J; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Zhao Z; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
  • Currie KS; Gilead Sciences, 36 East Industrial Rd., Branford, CT 06405, United States (formerly CGI Pharmaceuticals).
Bioorg Med Chem Lett ; 25(6): 1333-7, 2015 Mar 15.
Article em En | MEDLINE | ID: mdl-25701252
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinonas / Tiofenos / Proteínas Tirosina Quinases / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinonas / Tiofenos / Proteínas Tirosina Quinases / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos