Review of the biological properties and toxicity of usnic acid.
Nat Prod Res
; 29(23): 2167-80, 2015.
Article
em En
| MEDLINE
| ID: mdl-25707417
ABSTRACT
Since its first isolation in 1844, usnic acid [2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bH)-dibenzo-furandione] has become the most extensively studied lichen metabolite and one of the few that are commercially available. Lichens belonging to usnic acid-containing genera have been used as crude drugs throughout the world. There are indications of usnic acid being a potentially interesting candidate for such activities as anti-inflammatory, analgesic, healing, antioxidant, antimicrobial, antiprotozoal, antiviral, larvicidal and UV protection. However, some studies reported the liver toxicity and contact allergy. Thus, further studies are needed to establish the efficacy and safety of usnic acid.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Benzofuranos
/
Líquens
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Brasil