Pancreatic adenocarcinoma upregulated factor (PAUF) confers resistance to pancreatic cancer cells against oncolytic parvovirus H-1 infection through IFNA receptor-mediated signaling.

Kaowinn, Sirichat; Cho, Il-Rae; Moon, Jeong; Jun, Seung Won; Kim, Chang Seok; Kang, Ho Young; Kim, Manbok; Koh, Sang Seok; Chung, Young-Hwa

Kaowinn, Sirichat; Cho, Il-Rae; Moon, Jeong; Jun, Seung Won; Kim, Chang Seok; Kang, Ho Young; Kim, Manbok; Koh, Sang Seok; Chung, Young-Hwa.

Afiliação

Kaowinn S; BK21+, Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-736, Republic of Korea.
Cho IR; BK21+, Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-736, Republic of Korea.
Moon J; BK21+, Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-736, Republic of Korea.
Jun SW; BK21+, Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-736, Republic of Korea.
Kim CS; BK21+, Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-736, Republic of Korea.
Kang HY; Department of Microbiology, Pusan National University, Busan 609-736, Republic of Korea.
Kim M; Department of Medical Science, Dankook University College of Medicine, Cheonan 330-714, Republic of Korea.
Koh SS; Department of Biological Sciences, Dong-A University, Busan 604-714, Republic of Korea.
Chung YH; BK21+, Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-736, Republic of Korea. Electronic address: younghc@pusan.ac.kr.

Biochem Biophys Res Commun ; 459(2): 313-318, 2015 Apr 03.

Article em En | MEDLINE | ID: mdl-25727013

Assuntos

Parvovirus H-1; Lectinas/metabolismo; Terapia Viral Oncolítica; Neoplasias Pancreáticas/metabolismo; Neoplasias Pancreáticas/terapia; Receptor de Interferon alfa e beta/metabolismo; Apoptose; Linhagem Celular Tumoral; Expressão Gênica; Humanos; Peptídeos e Proteínas de Sinalização Intercelular; Lectinas/antagonistas & inibidores; Lectinas/genética; Neoplasias Pancreáticas/genética; Infecções por Parvoviridae/genética; Infecções por Parvoviridae/metabolismo; Infecções por Parvoviridae/patologia; RNA Interferente Pequeno/genética; Receptor de Interferon alfa e beta/genética; Fator de Transcrição STAT1/antagonistas & inibidores; Fator de Transcrição STAT1/genética; Fator de Transcrição STAT1/metabolismo; Transdução de Sinais; TYK2 Quinase/antagonistas & inibidores; TYK2 Quinase/genética; TYK2 Quinase/metabolismo

Palavras-chave

H-1 virus; IFNAR; PAUF; Stat1; Tyk2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Terapia Viral Oncolítica / Parvovirus H-1 / Receptor de Interferon alfa e beta / Lectinas Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2015 Tipo de documento: Article

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