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Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM.
Chromikova, Veronika; Mader, Alexander; Hofbauer, Stefan; Göbl, Christoph; Madl, Tobias; Gach, Johannes S; Bauernfried, Stefan; Furtmüller, Paul G; Forthal, Donald N; Mach, Lukas; Obinger, Christian; Kunert, Renate.
Afiliação
  • Chromikova V; Department of Biotechnology, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Mader A; Department of Biotechnology, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Hofbauer S; Department of Chemistry, Division of Biochemistry, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria; Department for Structural and Computational Biology, Max F. Perutz Laboratories, University of Vienna, Austria.
  • Göbl C; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR Spectroscopy, Department of Chemistry, Technical University Munich, Garching, Germany; Institute of Structural Biology, Helmholtz Center Munich, Neuherberg, Germany.
  • Madl T; Center for Integrated Protein Science Munich at Chair of Biomolecular NMR Spectroscopy, Department of Chemistry, Technical University Munich, Garching, Germany; Institute of Structural Biology, Helmholtz Center Munich, Neuherberg, Germany; Institute of Molecular Biology and Biochemistry, Center of M
  • Gach JS; Department of Medicine, Division of Infectious Diseases, University of CA, Irvine, USA.
  • Bauernfried S; Department of Biotechnology, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Furtmüller PG; Department of Chemistry, Division of Biochemistry, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Forthal DN; Department of Medicine, Division of Infectious Diseases, University of CA, Irvine, USA.
  • Mach L; Department of Applied Genetics and Cell Biology, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria.
  • Obinger C; Department of Chemistry, Division of Biochemistry, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria. Electronic address: christian.obinger@boku.ac.at.
  • Kunert R; Department of Biotechnology, Vienna Institute of BioTechnology at BOKU, University of Natural Resources and Life Sciences, Vienna, Austria. Electronic address: renate.kunert@boku.ac.at.
Biochim Biophys Acta ; 1854(10 Pt A): 1536-44, 2015 Oct.
Article em En | MEDLINE | ID: mdl-25748881
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina M / Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Anticorpos Monoclonais Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Áustria
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina M / Anticorpos Anti-HIV / Proteína gp120 do Envelope de HIV / HIV-1 / Anticorpos Monoclonais Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Áustria