Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition.

Liu, Hong; Ren, Guoping; Wang, Tingyang; Chen, Yuexia; Gong, Chaoju; Bai, Yanfeng; Wang, Bo; Qi, Hongyan; Shen, Jing; Zhu, Lijun; Qian, Cheng; Lai, Maode; Shao, Jimin

Liu, Hong; Ren, Guoping; Wang, Tingyang; Chen, Yuexia; Gong, Chaoju; Bai, Yanfeng; Wang, Bo; Qi, Hongyan; Shen, Jing; Zhu, Lijun; Qian, Cheng; Lai, Maode; Shao, Jimin.

Afiliação

Liu H; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Ren G; Department of Pathology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Wang T; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Chen Y; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Gong C; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Bai Y; Department of Pathology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Wang B; Department of Pathology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Qi H; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Shen J; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Zhu L; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Qian C; Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Lai M; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China.
Shao J; Department of Pathology and Pathophysiology, Zhejiang Key Laboratory for Disease Proteomics, Zhejiang University School of Medicine, Hangzhou 310058, China, shaojimin@zju.edu.cn.

Carcinogenesis ; 36(4): 459-68, 2015 Apr.

Article em En | MEDLINE | ID: mdl-25750173

Assuntos

Neoplasias Colorretais/genética; Transição Epitelial-Mesenquimal/genética; Interleucina-6/genética; Proteínas Proto-Oncogênicas c-fos/genética; Fator de Transcrição STAT3/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Proteínas de Ligação a DNA; Regulação Neoplásica da Expressão Gênica; Células HEK293; Células HT29; Humanos; Interleucina-6/metabolismo; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/secundário; Metástase Linfática/genética; Ligação Proteica; Processamento de Proteína Pós-Traducional; Proteínas Proto-Oncogênicas c-fos/biossíntese; Interferência de RNA; RNA Interferente Pequeno; Fator de Transcrição STAT3/metabolismo; Transdução de Sinais/genética; Ativação Transcricional/genética; Microambiente Tumoral

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Interleucina-6 / Proteínas Proto-Oncogênicas c-fos / Fator de Transcrição STAT3 / Transição Epitelial-Mesenquimal Limite: Humans Idioma: En Revista: Carcinogenesis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google