Social vulnerability and survival across levels of frailty in the Honolulu-Asia Aging Study.
Age Ageing
; 44(4): 709-12, 2015 Jul.
Article
em En
| MEDLINE
| ID: mdl-25758407
ABSTRACT
PURPOSE:
we evaluated mortality risk in relation to social vulnerability across levels of frailty among a cohort of older Japanese-American men.METHODS:
in secondary analysis of the Honolulu-Asia Aging Study (HAAS), participants (n = 3,271) were aged 72-93 years at baseline. A frailty index (FI) created using 58 potential health deficits to quantify participants' frailty level at baseline, with four frailty strata 0.0 < FI ≤ 0.1 (n = 1,074); 0.1 < FI ≤ 0.20 (n = 1,549); 0.2 < FI ≤ 0.30 (n = 472); FI > 0.3 (n = 176). Similarly, a social vulnerability index was created using 19 self-reported social deficits. Cox proportional hazard modelling was employed to estimate the impact of social vulnerability across the four levels of frailty, accounting for age, smoking, alcohol use and variation in health deficits within each frailty level.RESULTS:
for the fittest participants, social vulnerability was associated with mortality (hazards ratio (HR) = 1.04, 95% confidence interval (CI) = 1.01, 1.07; P value = 0.008). Similarly, for those considered at risk for frailty, each social deficit was associated with a 5% increased risk of mortality. For frail individuals, the Cox regression analyses indicated that social vulnerability was not significantly associated with mortality (0.2 < FI ≤ 0.3 HR = 1.016, 95% CI = 0.98, 1.06; P value = 0.442; FI > 0.3 HR = 0.98, 95% CI = 0.93, 1.04).CONCLUSIONS:
for the fittest and at-risk HAAS participants, the accumulation of social deficits was associated with significant increases in mortality risk. For frail individuals (FI > 0.20), the estimation of mortality risk may depend more so on intrinsic factors related to their health.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Envelhecimento
/
Asiático
/
Avaliação Geriátrica
/
Idoso Fragilizado
/
Medição de Risco
/
Populações Vulneráveis
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
País/Região como assunto:
Caribe ingles
/
Jamaica
Idioma:
En
Revista:
Age Ageing
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Canadá