Induction of interferon-stimulated genes by IRF3 promotes replication of Toxoplasma gondii.

Majumdar, Tanmay; Chattopadhyay, Saurabh; Ozhegov, Evgeny; Dhar, Jayeeta; Goswami, Ramansu; Sen, Ganes C; Barik, Sailen

Majumdar, Tanmay; Chattopadhyay, Saurabh; Ozhegov, Evgeny; Dhar, Jayeeta; Goswami, Ramansu; Sen, Ganes C; Barik, Sailen.

Afiliação

Majumdar T; Center for Gene Regulation in Health and Disease, and Department of Biological, Geological and Environmental Sciences, College of Sciences and Health Professions, Cleveland State University, Cleveland, Ohio, United States of America.
Chattopadhyay S; Department of Molecular Genetics, Lerner Research Institute of the Cleveland Clinic, Cleveland, Ohio, United States of America.
Ozhegov E; Center for Gene Regulation in Health and Disease, and Department of Biological, Geological and Environmental Sciences, College of Sciences and Health Professions, Cleveland State University, Cleveland, Ohio, United States of America.
Dhar J; Center for Gene Regulation in Health and Disease, and Department of Biological, Geological and Environmental Sciences, College of Sciences and Health Professions, Cleveland State University, Cleveland, Ohio, United States of America.
Goswami R; Center for Gene Regulation in Health and Disease, and Department of Biological, Geological and Environmental Sciences, College of Sciences and Health Professions, Cleveland State University, Cleveland, Ohio, United States of America.
Sen GC; Department of Molecular Genetics, Lerner Research Institute of the Cleveland Clinic, Cleveland, Ohio, United States of America.
Barik S; Center for Gene Regulation in Health and Disease, and Department of Biological, Geological and Environmental Sciences, College of Sciences and Health Professions, Cleveland State University, Cleveland, Ohio, United States of America.

PLoS Pathog ; 11(3): e1004779, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25811886

Assuntos

Fator Regulador 3 de Interferon/imunologia; Transdução de Sinais/imunologia; Toxoplasma/imunologia; Toxoplasmose/imunologia; Animais; Proteína DEAD-box 58; RNA Helicases DEAD-box/genética; RNA Helicases DEAD-box/imunologia; Técnicas de Silenciamento de Genes; Células HEK293; Humanos; Fator Regulador 3 de Interferon/genética; Proteínas de Membrana/genética; Proteínas de Membrana/imunologia; Camundongos; Camundongos Knockout; Proteínas Serina-Treonina Quinases/genética; Proteínas Serina-Treonina Quinases/imunologia; Receptores Imunológicos; Transdução de Sinais/genética; Toxoplasmose/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxoplasma / Transdução de Sinais / Toxoplasmose / Fator Regulador 3 de Interferon Limite: Animals / Humans Idioma: En Revista: PLoS Pathog Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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