Development of a novel carrier optimized for cell sheet transplantation.
Biomatter
; 5: e1027846, 2015.
Article
em En
| MEDLINE
| ID: mdl-25869322
ABSTRACT
Tissue engineering is a rapidly advancing technology in the field of regenerative medicine. For the transplantation of cell sheets, a carrier must maintain the shape of a cell sheet from a culture dish to affected sites as well as release the sheet easily onto the lesion. In this study, we examined the utility of a novel, poly(lactic acid)-based carrier for cell sheets transplantation to the cornea of dogs and the skin of rats. The poly(lactic acid)-based carrier easily picked a cell sheet up from the dish, fit to the shape of the transplantation sites, and saved time for cell sheets detachment comparing to a conventional carrier. Thus, the poly(lactic acid)-based carrier would be useful for easy cell sheet transplantations.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Pele
/
Transplante de Células
/
Ácido Láctico
/
Lesões da Córnea
Limite:
Animals
Idioma:
En
Revista:
Biomatter
Ano de publicação:
2015
Tipo de documento:
Article