Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia.

Yang, Xinan Holly; Li, Meiyi; Wang, Bin; Zhu, Wanqi; Desgardin, Aurelie; Onel, Kenan; de Jong, Jill; Chen, Jianjun; Chen, Luonan; Cunningham, John M

Yang, Xinan Holly; Li, Meiyi; Wang, Bin; Zhu, Wanqi; Desgardin, Aurelie; Onel, Kenan; de Jong, Jill; Chen, Jianjun; Chen, Luonan; Cunningham, John M.

Afiliação

Yang XH; Department of Pediatrics, and Comer Children's Hospital, Section of Hematology/Oncology, The University of Chicago, 900 East 57th Street, KCBD Room 5121, Chicago, Illinois, 60637, USA. xyang2@uchicago.edu.
Li M; Key Laboratory of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. limeiyi@sibs.ac.cn.
Wang B; Department of Pediatrics, and Comer Children's Hospital, Section of Hematology/Oncology, The University of Chicago, 900 East 57th Street, KCBD Room 5121, Chicago, Illinois, 60637, USA. bwang@peds.bsd.uchicago.edu.
Zhu W; Laboratory Schools, The University of Chicago, Chicago, USA. 1213.ghs@gmail.com.
Desgardin A; Department of Pediatrics, and Comer Children's Hospital, Section of Hematology/Oncology, The University of Chicago, 900 East 57th Street, KCBD Room 5121, Chicago, Illinois, 60637, USA. adesgard@bsd.uchicago.edu.
Onel K; Department of Pediatrics, and Comer Children's Hospital, Section of Hematology/Oncology, The University of Chicago, 900 East 57th Street, KCBD Room 5121, Chicago, Illinois, 60637, USA. konel@peds.bsd.uchicago.edu.
de Jong J; Department of Pediatrics, and Comer Children's Hospital, Section of Hematology/Oncology, The University of Chicago, 900 East 57th Street, KCBD Room 5121, Chicago, Illinois, 60637, USA. jdejong@peds.bsd.uchicago.edu.
Chen J; Department of Medicine, The University of Chicago, Chicago, USA. jchen@medicine.bsd.uchicago.edu.
Chen L; Key Laboratory of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. lnchen@sibs.ac.cn.
Cunningham JM; Department of Pediatrics, and Comer Children's Hospital, Section of Hematology/Oncology, The University of Chicago, 900 East 57th Street, KCBD Room 5121, Chicago, Illinois, 60637, USA. jmcunningham@uchicago.edu.

BMC Bioinformatics ; 16: 97, 2015 Mar 24.

Article em En | MEDLINE | ID: mdl-25887548

Assuntos

Redes Reguladoras de Genes; Células-Tronco Hematopoéticas/metabolismo; Leucemia Mieloide Aguda/genética; Células-Tronco Neoplásicas/metabolismo; Transcriptoma; Algoritmos; Perfilação da Expressão Gênica; Humanos; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/mortalidade; Prognóstico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Células-Tronco Hematopoéticas / Leucemia Mieloide Aguda / Redes Reguladoras de Genes / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: BMC Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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