Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension.
BMC Pulm Med
; 15: 11, 2015 Feb 13.
Article
em En
| MEDLINE
| ID: mdl-25888026
ABSTRACT
BACKGROUND:
Patients with precapillary pulmonary hypertension (PH) have been reported to suffer from poor sleep quality, however, if this is related to physical exercise performance has not yet been thoroughly investigated.METHODS:
Clinically stable out-patients with idiopathic pulmonary arterial hypertension (IPAH, n = 52) and chronic thromboembolic PH (CTEPH, n = 64) in NYHA classes II and III were prospectively enrolled. 54 healthy volunteers matched for anthropometric variables served as a control group. The Pittsburgh Sleep Quality Index (PSQI) was used to rate subjective sleep quality. In the PH patients, six-minute walk tests (6MWT) were performed to assess exercise capacity.RESULTS:
Poor sleep quality (i.e. a PSQI score > 5) occurred more frequently in PH (IPAH n = 25 [48.1%], CTEPH n = 39 [60.9%], controls n = 10 [18.5%]; p < 0.01 when compared to controls). In addition, poor vs. good sleepers had significantly higher average NYHA class (IPAH 2.6 ± 0.1 vs. 2.3 ± 0.1, CTEPH 2.8 ± 0.1 vs. 2.3 ± 0.2; p < 0.01) and shorter 6MWT distances (IPAH 338 ± 23 vs. 441 ± 29 m, CTEPH 355 ± 15 vs. 413 ± 26 m; p < 0.05).CONCLUSIONS:
Self-reported poor sleep quality is more common in PH than in healthy controls. Furthermore, it is related to reduced physical exercise capacity.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Embolia Pulmonar
/
Sono
/
Transtornos do Sono-Vigília
/
Tolerância ao Exercício
/
Hipertensão Pulmonar Primária Familiar
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
BMC Pulm Med
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Alemanha