Mineralocorticoid and apparent mineralocorticoid syndromes of secondary hypertension.
Adv Chronic Kidney Dis
; 22(3): 185-95, 2015 May.
Article
em En
| MEDLINE
| ID: mdl-25908467
ABSTRACT
The mineralocorticoid aldosterone is a key hormone in the regulation of plasma volume and blood pressure in man. Excessive levels of this mineralocorticoid have been shown to mediate metabolic disorders and end-organ damage more than what can be attributed to its effects on blood pressure alone. Inappropriate excess levels of aldosterone contribute significantly to the cardiorenal metabolic syndrome and target organ injury that include atherosclerosis, myocardial hypertrophy, fibrosis, heart failure, and kidney disease. The importance of understanding the role of excess mineralocorticoid hormones such as aldosterone in resistant hypertension and in those with secondary hypertension should be visited. Primary aldosteronism is one of the commonly identified causes of hypertension and is treatable and/or potentially curable. We intend to review the management of mineralocorticoid-induced hypertension in the adult population along with other disease entities that mimic primary aldosteronism.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Córtex Suprarrenal
/
Hiperplasia Suprarrenal Congênita
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Adenoma Adrenocortical
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Antagonistas de Receptores de Mineralocorticoides
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Hiperaldosteronismo
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Hipertensão
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
Adv Chronic Kidney Dis
Assunto da revista:
NEFROLOGIA
Ano de publicação:
2015
Tipo de documento:
Article