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Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor.
Spurny, Radovan; Debaveye, Sarah; Farinha, Ana; Veys, Ken; Vos, Ann M; Gossas, Thomas; Atack, John; Bertrand, Sonia; Bertrand, Daniel; Danielson, U Helena; Tresadern, Gary; Ulens, Chris.
Afiliação
  • Spurny R; Laboratory of Structural Neurobiology, Katholieke Universiteit Leuven, Leuven B-3000, Belgium;
  • Debaveye S; Laboratory of Structural Neurobiology, Katholieke Universiteit Leuven, Leuven B-3000, Belgium;
  • Farinha A; Laboratory of Structural Neurobiology, Katholieke Universiteit Leuven, Leuven B-3000, Belgium;
  • Veys K; Neurosciences and.
  • Vos AM; Discovery Sciences, Janssen Research and Development, Beerse B-2340, Belgium;
  • Gossas T; Beactica AB, SE-752 37 Uppsala, Sweden;
  • Atack J; Translational Drug Discovery Group, University of Sussex, BN1 9QJ Brighton, United Kingdom;
  • Bertrand S; HiQscreen,1222 Vésenaz, Geneva, Switzerland; and.
  • Bertrand D; HiQscreen,1222 Vésenaz, Geneva, Switzerland; and.
  • Danielson UH; Beactica AB, SE-752 37 Uppsala, Sweden; Department of Chemistry, Uppsala Biomedical Center, Uppsala University, SE-751 23 Uppsala, Sweden.
  • Tresadern G; Discovery Sciences, Janssen Research and Development, Beerse B-2340, Belgium;
  • Ulens C; Laboratory of Structural Neurobiology, Katholieke Universiteit Leuven, Leuven B-3000, Belgium; chris.ulens@med.kuleuven.be.
Proc Natl Acad Sci U S A ; 112(19): E2543-52, 2015 May 12.
Article em En | MEDLINE | ID: mdl-25918415
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sítio Alostérico / Receptor Nicotínico de Acetilcolina alfa7 Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sítio Alostérico / Receptor Nicotínico de Acetilcolina alfa7 Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article