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Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?
De Carolis, S; Botta, A; Salvi, S; di Pasquo, E; Del Sordo, G; Garufi, C; Lanzone, A; De Carolis, M P.
Afiliação
  • De Carolis S; Department of Obstetrics and Gynecology, Catholic University of Rome, Italy.
  • Botta A; Department of Obstetrics and Gynecology, Catholic University of Rome, Italy.
  • Salvi S; Department of Obstetrics and Gynecology, Catholic University of Rome, Italy.
  • di Pasquo E; Department of Obstetrics and Gynecology, Catholic University of Rome, Italy. Electronic address: elviradp1@hotmail.it.
  • Del Sordo G; Department of Obstetrics and Gynecology, Catholic University of Rome, Italy.
  • Garufi C; Department of Obstetrics and Gynecology, Catholic University of Rome, Italy.
  • Lanzone A; Department of Obstetrics and Gynecology, Catholic University of Rome, Italy.
  • De Carolis MP; Department of Neonatology, Catholic University of Rome, Italy.
Autoimmun Rev ; 14(9): 760-2, 2015 Sep.
Article em En | MEDLINE | ID: mdl-25936295
ABSTRACT
The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Antifosfolipídica / Hidroxicloroquina Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Autoimmun Rev Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Antifosfolipídica / Hidroxicloroquina Limite: Adult / Female / Humans / Pregnancy Idioma: En Revista: Autoimmun Rev Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Itália