Curcumin regulates cell fate and metabolism by inhibiting hedgehog signaling in hepatic stellate cells.

Lian, Naqi; Jiang, Yuanyuan; Zhang, Feng; Jin, Huanhuan; Lu, Chunfeng; Wu, Xiafei; Lu, Yin; Zheng, Shizhong

Lian, Naqi; Jiang, Yuanyuan; Zhang, Feng; Jin, Huanhuan; Lu, Chunfeng; Wu, Xiafei; Lu, Yin; Zheng, Shizhong.

Afiliação

Lian N; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Jiang Y; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Zhang F; 1] Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China [2] Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China [3] The National First-Class Key Discipline fo
Jin H; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Lu C; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Wu X; Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Lu Y; 1] Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China [2] Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China [3] The National First-Class Key Discipline fo
Zheng S; 1] Department of Pharmacology, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China [2] Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China [3] The National First-Class Key Discipline fo

Lab Invest ; 95(7): 790-803, 2015 Jul.

Article em En | MEDLINE | ID: mdl-25938627

Assuntos

Antineoplásicos/farmacologia; Curcumina/farmacologia; Proteínas Hedgehog/metabolismo; Células Estreladas do Fígado/efeitos dos fármacos; Cirrose Hepática/tratamento farmacológico; Animais; Antineoplásicos/uso terapêutico; Apoptose/efeitos dos fármacos; Curcuma; Curcumina/uso terapêutico; Glicólise/efeitos dos fármacos; Células Estreladas do Fígado/metabolismo; Cirrose Hepática/metabolismo; Masculino; Receptores Patched; Fitoterapia; Distribuição Aleatória; Ratos Sprague-Dawley; Receptores de Superfície Celular/metabolismo; Receptores Acoplados a Proteínas G/metabolismo; Receptor Smoothened

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Curcumina / Proteínas Hedgehog / Células Estreladas do Fígado / Cirrose Hepática / Antineoplásicos Limite: Animals Idioma: En Revista: Lab Invest Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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