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KU675, a Concomitant Heat-Shock Protein Inhibitor of Hsp90 and Hsc70 that Manifests Isoform Selectivity for Hsp90α in Prostate Cancer Cells.
Liu, Weiya; Vielhauer, George A; Holzbeierlein, Jeffrey M; Zhao, Huiping; Ghosh, Suman; Brown, Douglas; Lee, Eugene; Blagg, Brian S J.
Afiliação
  • Liu W; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.).
  • Vielhauer GA; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.).
  • Holzbeierlein JM; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.) jholzbeierlein@kumc.edu bblagg@ku.edu.
  • Zhao H; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.).
  • Ghosh S; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.).
  • Brown D; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.).
  • Lee E; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.).
  • Blagg BS; Department of Urology, University of Kansas Medical Center, Kansas City, Kansas (W.L., G.A.V., J.M.H., D.B., E.L.); and Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas (H.Z., S.G., B.S.J.B.) jholzbeierlein@kumc.edu bblagg@ku.edu.
Mol Pharmacol ; 88(1): 121-30, 2015 Jul.
Article em En | MEDLINE | ID: mdl-25939977
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Neoplasias da Próstata / Novobiocina / Proteínas de Choque Térmico HSP90 / Cumarínicos / Proteínas de Choque Térmico HSC70 / Antineoplásicos Limite: Humans / Male Idioma: En Revista: Mol Pharmacol Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Neoplasias da Próstata / Novobiocina / Proteínas de Choque Térmico HSP90 / Cumarínicos / Proteínas de Choque Térmico HSC70 / Antineoplásicos Limite: Humans / Male Idioma: En Revista: Mol Pharmacol Ano de publicação: 2015 Tipo de documento: Article