Modulation of stratum corneum lipid composition and organization of human skin equivalents by specific medium supplements.

Thakoersing, Varsha S; van Smeden, Jeroen; Boiten, Walter A; Gooris, Gert S; Mulder, Aat A; Vreeken, Rob J; El Ghalbzouri, Abdoelwaheb; Bouwstra, Joke A

Thakoersing, Varsha S; van Smeden, Jeroen; Boiten, Walter A; Gooris, Gert S; Mulder, Aat A; Vreeken, Rob J; El Ghalbzouri, Abdoelwaheb; Bouwstra, Joke A.

Afiliação

Thakoersing VS; Department of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
van Smeden J; Department of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Boiten WA; Department of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Gooris GS; Department of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Mulder AA; Department of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Vreeken RJ; Department of Analytical Biosciences, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
El Ghalbzouri A; Netherlands Metabolomics Centre, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Bouwstra JA; Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands.

Exp Dermatol ; 24(9): 669-74, 2015 Sep.

Article em En | MEDLINE | ID: mdl-25939986

Assuntos

Meios de Cultura/farmacologia; Epiderme/efeitos dos fármacos; Ácidos Graxos Monoinsaturados/análise; Metabolismo dos Lipídeos/efeitos dos fármacos; Ácido Palmítico/farmacologia; Células Cultivadas; Ácidos Eicosanoicos/metabolismo; Ácidos Eicosanoicos/farmacologia; Epiderme/química; Epiderme/metabolismo; Ácidos Graxos Monoinsaturados/metabolismo; Humanos; Queratinócitos; Modelos Biológicos; Ácido Palmítico/química; Ácido Palmítico/metabolismo; Fenômenos Fisiológicos da Pele/efeitos dos fármacos; Pele Artificial; Técnicas de Cultura de Tecidos

Palavras-chave

deuterated lipids; fatty acids; lipid organization; skin barrier; stratum corneum

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Graxos Monoinsaturados / Ácido Palmítico / Meios de Cultura / Epiderme / Metabolismo dos Lipídeos Limite: Humans Idioma: En Revista: Exp Dermatol Assunto da revista: DERMATOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda

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