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Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs.
Ninomiya, Soranobu; Narala, Neeharika; Huye, Leslie; Yagyu, Shigeki; Savoldo, Barbara; Dotti, Gianpietro; Heslop, Helen E; Brenner, Malcolm K; Rooney, Cliona M; Ramos, Carlos A.
Afiliação
  • Ninomiya S; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and.
  • Narala N; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and.
  • Huye L; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and.
  • Yagyu S; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and.
  • Savoldo B; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and Departments of Pediatrics.
  • Dotti G; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and Medicine, and.
  • Heslop HE; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and Departments of Pediatrics, Medicine, and.
  • Brenner MK; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and Departments of Pediatrics, Medicine, and.
  • Rooney CM; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and Departments of Pediatrics, Pathology and Immunology, and Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX.
  • Ramos CA; Center for Cell and Gene Therapy, Houston Methodist Hospital, Texas Children's Hospital, and Baylor College of Medicine, Houston, TX; and Medicine, and.
Blood ; 125(25): 3905-16, 2015 Jun 18.
Article em En | MEDLINE | ID: mdl-25940712

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígenos CD19 / Indolamina-Pirrol 2,3,-Dioxigenase / Imunoterapia / Linfoma Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígenos CD19 / Indolamina-Pirrol 2,3,-Dioxigenase / Imunoterapia / Linfoma Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2015 Tipo de documento: Article