Acrylic bone cements: the role of nanotechnology in improving osteointegration and tunable mechanical properties.
J Biomed Nanotechnol
; 10(12): 3536-57, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-26000369
ABSTRACT
Nanotechnology is an extremely powerful emerging technology, which is expected to have a substantial impact on biomedical technology, especially in tissue engineering and drug delivery. The use of nanocompounds and nanoparticles in the synthesis of improved bone cements to be applied in vertebroplasty/kyphoplasty and arthroplasty, is of great interest due to the increasing incidence of osteoporosis and osteoarthritis. This review reports new advances in the development of acrylic bone cements, using different radio-opalescent nanomaterials taking into consideration their influence on the mechanical behavior and biocompatibility of the resulting acrylic bone cement. Furthermore, other non-radiopaque nanoparticles capable of mechanically reinforcing the bone cement as well as induce osteointegration, are also reviewed. Additionally, nanoparticles used to improve the controlled release of antibiotics contained in acrylic bone cements are briefly described.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osseointegração
/
Polimetil Metacrilato
/
Nanopartículas
/
Cementoplastia
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Biomed Nanotechnol
Ano de publicação:
2014
Tipo de documento:
Article