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Ghrelin.
Müller, T D; Nogueiras, R; Andermann, M L; Andrews, Z B; Anker, S D; Argente, J; Batterham, R L; Benoit, S C; Bowers, C Y; Broglio, F; Casanueva, F F; D'Alessio, D; Depoortere, I; Geliebter, A; Ghigo, E; Cole, P A; Cowley, M; Cummings, D E; Dagher, A; Diano, S; Dickson, S L; Diéguez, C; Granata, R; Grill, H J; Grove, K; Habegger, K M; Heppner, K; Heiman, M L; Holsen, L; Holst, B; Inui, A; Jansson, J O; Kirchner, H; Korbonits, M; Laferrère, B; LeRoux, C W; Lopez, M; Morin, S; Nakazato, M; Nass, R; Perez-Tilve, D; Pfluger, P T; Schwartz, T W; Seeley, R J; Sleeman, M; Sun, Y; Sussel, L; Tong, J; Thorner, M O; van der Lely, A J.
Afiliação
  • Müller TD; Institute for Diabetes and Obesity, Helmholtz Zentrum München, München, Germany.
  • Nogueiras R; Department of Physiology, Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, University of Santiago de Compostela (CIMUS)-Instituto de Investigación Sanitaria (IDIS)-CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain.
  • Andermann ML; Division of Endocrinology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
  • Andrews ZB; Department of Physiology, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.
  • Anker SD; Applied Cachexia Research, Department of Cardiology, Charité Universitätsmedizin Berlin, Germany.
  • Argente J; Department of Pediatrics and Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain ; Department of Pediatrics, Universidad Autónoma de Madrid and CIBER Fisiopatología de la obesidad y nutrición, Instituto de Salud Carlos III, Madri
  • Batterham RL; Centre for Obesity Research, University College London, London, United Kingdom.
  • Benoit SC; Metabolic Disease Institute, Division of Endocrinology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Bowers CY; Tulane University Health Sciences Center, Endocrinology and Metabolism Section, Peptide Research Section, New Orleans, LA, USA.
  • Broglio F; Division of Endocrinology, Diabetes and Metabolism, Dept. of Medical Sciences, University of Torino, Torino, Italy.
  • Casanueva FF; Department of Medicine, Santiago de Compostela University, Complejo Hospitalario Universitario de Santiago (CHUS), CIBER de Fisiopatologia Obesidad y Nutricion (CB06/03), Instituto Salud Carlos III, Santiago de Compostela, Spain.
  • D'Alessio D; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA.
  • Depoortere I; Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, Belgium.
  • Geliebter A; New York Obesity Nutrition Research Center, Department of Medicine, St Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY, USA.
  • Ghigo E; Department of Pharmacology & Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Cole PA; Monash Obesity & Diabetes Institute, Monash University, Clayton, Victoria, Australia.
  • Cowley M; Department of Physiology, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia ; Monash Obesity & Diabetes Institute, Monash University, Clayton, Victoria, Australia.
  • Cummings DE; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
  • Dagher A; McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
  • Diano S; Dept of Neurobiology, Yale University School of Medicine, New Haven, CT, USA.
  • Dickson SL; Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
  • Diéguez C; Department of Physiology, School of Medicine, Instituto de Investigacion Sanitaria (IDIS), University of Santiago de Compostela, Spain.
  • Granata R; Division of Endocrinology, Diabetes and Metabolism, Dept. of Medical Sciences, University of Torino, Torino, Italy.
  • Grill HJ; Department of Psychology, Institute of Diabetes, Obesity and Metabolism, University of Pennsylvania, Philadelphia, PA, USA.
  • Grove K; Department of Diabetes, Obesity and Metabolism, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Habegger KM; Comprehensive Diabetes Center, University of Alabama School of Medicine, Birmingham, AL, USA.
  • Heppner K; Division of Diabetes, Obesity, and Metabolism, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR 97006, USA.
  • Heiman ML; NuMe Health, 1441 Canal Street, New Orleans, LA 70112, USA.
  • Holsen L; Departments of Psychiatry and Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Holst B; Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen N, Denmark.
  • Inui A; Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
  • Jansson JO; Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
  • Kirchner H; Medizinische Klinik I, Universitätsklinikum Schleswig-Holstein Campus Lübeck, Lübeck, Germany.
  • Korbonits M; Centre for Endocrinology, William Harvey Research Institute, Barts and the London, Queen Mary University of London, London, UK.
  • Laferrère B; New York Obesity Research Center, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.
  • LeRoux CW; Diabetes Complications Research Centre, Conway Institute, University College Dublin, Ireland.
  • Lopez M; Department of Physiology, Centro de Investigación en Medicina Molecular y Enfermedades Crónicas, University of Santiago de Compostela (CIMUS)-Instituto de Investigación Sanitaria (IDIS)-CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain.
  • Morin S; Institute for Diabetes and Obesity, Helmholtz Zentrum München, München, Germany.
  • Nakazato M; Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan.
  • Nass R; Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, VA, USA.
  • Perez-Tilve D; Department of Internal Medicine, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
  • Pfluger PT; Institute for Diabetes and Obesity, Helmholtz Zentrum München, München, Germany.
  • Schwartz TW; Department of Neuroscience and Pharmacology, Laboratory for Molecular Pharmacology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark.
  • Seeley RJ; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI, USA.
  • Sleeman M; Department of Physiology, Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.
  • Sun Y; Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
  • Sussel L; Department of Genetics and Development, Columbia University, New York, NY, USA.
  • Tong J; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA.
  • Thorner MO; Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, VA, USA.
  • van der Lely AJ; Department of Medicine, Erasmus University MC, Rotterdam, The Netherlands.
Mol Metab ; 4(6): 437-60, 2015 Jun.
Article em En | MEDLINE | ID: mdl-26042199
BACKGROUND: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. SCOPE OF REVIEW: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. MAJOR CONCLUSIONS: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Metab Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Metab Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha