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Correlation between Density of CD8+ T-cell Infiltrate in Microsatellite Unstable Colorectal Cancers and Frameshift Mutations: A Rationale for Personalized Immunotherapy.
Maby, Pauline; Tougeron, David; Hamieh, Mohamad; Mlecnik, Bernhard; Kora, Hafid; Bindea, Gabriela; Angell, Helen K; Fredriksen, Tessa; Elie, Nicolas; Fauquembergue, Emilie; Drouet, Aurélie; Leprince, Jérôme; Benichou, Jacques; Mauillon, Jacques; Le Pessot, Florence; Sesboüé, Richard; Tuech, Jean-Jacques; Sabourin, Jean-Christophe; Michel, Pierre; Frébourg, Thierry; Galon, Jérôme; Latouche, Jean-Baptiste.
Afiliação
  • Maby P; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France.
  • Tougeron D; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France. Department of Gastroenterology, Poitiers University Hospital, Poitiers, France. Laboratoire Inflammation Tissus Epithéliaux et Cytokines, Poitiers University, Poitiers, France.
  • Hamieh M; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France.
  • Mlecnik B; Inserm U1138, Laboratory of Integrative Cancer Immunology, Paris, France. Université Paris Descartes, Paris, France. Cordeliers Research Centre, Université Pierre et Marie Curie, Paris 6, Paris, France.
  • Kora H; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France.
  • Bindea G; Inserm U1138, Laboratory of Integrative Cancer Immunology, Paris, France. Université Paris Descartes, Paris, France. Cordeliers Research Centre, Université Pierre et Marie Curie, Paris 6, Paris, France.
  • Angell HK; Inserm U1138, Laboratory of Integrative Cancer Immunology, Paris, France. Université Paris Descartes, Paris, France. Cordeliers Research Centre, Université Pierre et Marie Curie, Paris 6, Paris, France. AstraZeneca Pharmaceuticals, Alderley Park, Cheshire, United Kingdom.
  • Fredriksen T; Inserm U1138, Laboratory of Integrative Cancer Immunology, Paris, France. Université Paris Descartes, Paris, France. Cordeliers Research Centre, Université Pierre et Marie Curie, Paris 6, Paris, France.
  • Elie N; Imaging Core Facility, CMABIO, Caen University Hospital, Caen, France.
  • Fauquembergue E; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France.
  • Drouet A; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France.
  • Leprince J; Inserm U982, Institute for Research and Innovation in Biomedicine (IRIB), Rouen University, France.
  • Benichou J; Biostatistics Unit, Inserm U657, Rouen University Hospital, Rouen University, Rouen, France.
  • Mauillon J; Department of Genetics, Rouen University Hospital, Rouen, France. Department of Gastroenterology, Le Havre Hospital, Le Havre, France.
  • Le Pessot F; Department of Pathology, Rouen University Hospital, Rouen, France.
  • Sesboüé R; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France.
  • Tuech JJ; Department of Digestive Surgery, Rouen University Hospital, Rouen, France.
  • Sabourin JC; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France. Department of Pathology, Rouen University Hospital, Rouen, France.
  • Michel P; Department of Gastroenterology, Rouen University Hospital, Rouen, France.
  • Frébourg T; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France. Department of Genetics, Rouen University Hospital, Rouen, France.
  • Galon J; Inserm U1138, Laboratory of Integrative Cancer Immunology, Paris, France. Université Paris Descartes, Paris, France. Cordeliers Research Centre, Université Pierre et Marie Curie, Paris 6, Paris, France.
  • Latouche JB; Inserm U1079, Institute for Research and Innovation in Biomedicine (IRIB), Rouen, France. Department of Genetics, Rouen University Hospital, Rouen, France. jean-baptiste.latouche@chu-rouen.fr.
Cancer Res ; 75(17): 3446-55, 2015 Sep 01.
Article em En | MEDLINE | ID: mdl-26060019
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Colorretais Hereditárias sem Polipose / Linfócitos do Interstício Tumoral / Instabilidade de Microssatélites Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Colorretais Hereditárias sem Polipose / Linfócitos do Interstício Tumoral / Instabilidade de Microssatélites Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: França