Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.

Østergaard, Søren D; Mukherjee, Shubhabrata; Sharp, Stephen J; Proitsi, Petroula; Lotta, Luca A; Day, Felix; Perry, John R B; Boehme, Kevin L; Walter, Stefan; Kauwe, John S; Gibbons, Laura E; Larson, Eric B; Powell, John F; Langenberg, Claudia; Crane, Paul K; Wareham, Nicholas J; Scott, Robert A

Østergaard, Søren D; Mukherjee, Shubhabrata; Sharp, Stephen J; Proitsi, Petroula; Lotta, Luca A; Day, Felix; Perry, John R B; Boehme, Kevin L; Walter, Stefan; Kauwe, John S; Gibbons, Laura E; Larson, Eric B; Powell, John F; Langenberg, Claudia; Crane, Paul K; Wareham, Nicholas J; Scott, Robert A.

Afiliação

Østergaard SD; Research Department P, Aarhus University Hospital, Risskov, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Mukherjee S; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Sharp SJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Proitsi P; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom.
Lotta LA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Day F; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Perry JR; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Boehme KL; Department of Biology, Brigham Young University, Provo, Utah, United States of America.
Walter S; Department of Epidemiology and Biostatistics, School of Medicine, University of California San Francisco, San Francisco, California, United States of America.
Kauwe JS; Department of Biology, Brigham Young University, Provo, Utah, United States of America.
Gibbons LE; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Larson EB; Department of Medicine, University of Washington, Seattle, Washington, United States of America; Group Health Research Institute, Seattle, Washington, United States of America.
Powell JF; Department of Basic and Clinical Neuroscience, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom.
Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Crane PK; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.

PLoS Med ; 12(6): e1001841; discussion e1001841, 2015 Jun.

Article em En | MEDLINE | ID: mdl-26079503

Assuntos

Doença de Alzheimer/genética; Análise da Randomização Mendeliana; Polimorfismo de Nucleotídeo Único; Feminino; Predisposição Genética para Doença; Humanos; Masculino; Fatores de Risco

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Análise da Randomização Mendeliana / Doença de Alzheimer Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Dinamarca

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