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Targeted Therapy for Breast Cancer Stem Cells by Liposomal Delivery of siRNA against Fibronectin EDB.
Sun, Yujin; Kim, Hoe Suk; Saw, Phei Er; Jon, Sangyong; Moon, Woo Kyung.
Afiliação
  • Sun Y; Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, South Korea.
  • Kim HS; Department of Radiology, Yanbian University Hospital, 1327 JuZi Street, Yanji City, JiLin Province, 133000, China.
  • Saw PE; Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, South Korea.
  • Jon S; Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701, South Korea.
  • Moon WK; Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701, South Korea.
Adv Healthc Mater ; 4(11): 1675-80, 2015 Aug 05.
Article em En | MEDLINE | ID: mdl-26097122
ABSTRACT
Targeted therapy for breast cancer stem cell (BCSC) A novel liposomal system (APTEDB -LS-siRNA(EDB) ) that enables simultaneous targeting and knockdown of extra domain B of fibronectin (EDB-FN) shows potent therapeutic efficacy in the BCSC-derived tumors in vivo.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Fibronectinas / RNA Interferente Pequeno / Lipossomos Limite: Animals / Female / Humans Idioma: En Revista: Adv Healthc Mater Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Coréia do Sul
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Fibronectinas / RNA Interferente Pequeno / Lipossomos Limite: Animals / Female / Humans Idioma: En Revista: Adv Healthc Mater Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Coréia do Sul