51Cr, Chromium-51; ALL, acute lymphoblastic leukemia; APC, allophycocyanin; APCs, antigen-presenting cells; Allo-HCT, allogeneic hematopoietic stem cell transplantation; BC, blast crisis; BLI, bioluminescence imaging; BM, bone marrow; BMDCs, bone marrow derived dendritic cells; BMT, bone marrow transplantation; CML, chronic myeloid leukemia; CRT, calreticulin; CTL, cytotoxic T cell; DCs, dendritic cells; FACS, Fluorescence-activated cell sorting; FBS, fatal bovine serum; FITC, fluorescein isothiocyanate; GVHD, graft-versus-host-disease; GVL, graft-versus-leukemia; HCT, hematopoietic stem cell transplantation; ICAM-1, intracellular adhesion molecule 1; Ik DN, Ikaros dominant negative; Ik, Ikaros; Ikaros; MACS, magnetic- activated cell sorting; MBL-2, moloney-murine sarcoma virus-induced MBL-2 lymphoma cells; MHC, major histocompatibility complex; MLR, mixed lymphocyte reaction; MiHAs, multiple minor histocompatibility antigens; PBS, phosphate buffered saline; PE, phycoerythrin; SIRP-α, signal regulatory protein α; TCD-BM, T cell depleted bone marrow; TSA, tumor specific antigen; Tregs, regulatory T cells; UCUCA, University Committee on Use and Care of Animals; WT, wild-type; antigen-presenting cells; bone marrow transplantation; graft-versus-leukemia; luc+, luciferase+; mAbs, monoclonal antibodies; mCRT, murine calreticulin