Loss of PHLPP protects against colitis by inhibiting intestinal epithelial cell apoptosis.

Wen, Yang-An; Li, Xin; Goretsky, Tatiana; Weiss, Heidi L; Barrett, Terrence A; Gao, Tianyan

Wen, Yang-An; Li, Xin; Goretsky, Tatiana; Weiss, Heidi L; Barrett, Terrence A; Gao, Tianyan.

Afiliação

Wen YA; Markey Cancer Center, University of Kentucky, Lexington, KY 40536-0509, USA.
Li X; Markey Cancer Center, University of Kentucky, Lexington, KY 40536-0509, USA.
Goretsky T; Division of Digestive Diseases and Nutrition, Department of Internal Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
Weiss HL; Markey Cancer Center, University of Kentucky, Lexington, KY 40536-0509, USA.
Barrett TA; Division of Digestive Diseases and Nutrition, Department of Internal Medicine, University of Kentucky, Lexington, KY 40536-0509, USA.
Gao T; Markey Cancer Center, University of Kentucky, Lexington, KY 40536-0509, USA; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY 40536-0509, USA. Electronic address: tianyan.gao@uky.edu.

Biochim Biophys Acta ; 1852(10 Pt A): 2013-23, 2015 Oct.

Article em En | MEDLINE | ID: mdl-26187040

Palavras-chave

Akt; Inflammatory bowel disease; Intestine epithelial cell apoptosis; Knockout mouse; PHLPP

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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