Ocotillol, a Majonoside R2 Metabolite, Ameliorates 2,4,6-Trinitrobenzenesulfonic Acid-Induced Colitis in Mice by Restoring the Balance of Th17/Treg Cells.

Lee, Sang-Yun; Jeong, Jin-Ju; Le, Thi Hong Van; Eun, Su-Hyeon; Nguyen, Minh Duc; Park, Jeong Hill; Kim, Dong-Hyun

Lee, Sang-Yun; Jeong, Jin-Ju; Le, Thi Hong Van; Eun, Su-Hyeon; Nguyen, Minh Duc; Park, Jeong Hill; Kim, Dong-Hyun.

Afiliação

Lee SY; Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, College of Pharmacy, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Korea.
Jeong JJ; Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, College of Pharmacy, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Korea.
Le TH; School of Pharmacy, University of Medicine and Pharmacy, 41 Dinh Tien Hoang Street, District 1, Ho Chi Minh City, Vietnam.
Eun SH; Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, College of Pharmacy, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Korea.
Nguyen MD; School of Pharmacy, University of Medicine and Pharmacy, 41 Dinh Tien Hoang Street, District 1, Ho Chi Minh City, Vietnam.
Park JH; §College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 1, Gwanak-ro, Gwanak-gu, 151-742, Seoul, Korea.
Kim DH; Department of Life and Nanopharmaceutical Sciences and Department of Pharmacy, College of Pharmacy, Kyung Hee University, 1, Hoegi, Dongdaemun-gu, Seoul 130-701, Korea.

J Agric Food Chem ; 63(31): 7024-31, 2015 Aug 12.

Article em En | MEDLINE | ID: mdl-26194345

Assuntos

Colite/tratamento farmacológico; Ginsenosídeos/administração & dosagem; Panax/química; Extratos Vegetais/administração & dosagem; Linfócitos T Reguladores/imunologia; Células Th17/imunologia; Animais; Colite/genética; Colite/imunologia; Humanos; Interleucina-17/genética; Interleucina-17/imunologia; Interleucina-1beta/genética; Interleucina-1beta/imunologia; Camundongos; Linfócitos T Reguladores/efeitos dos fármacos; Células Th17/efeitos dos fármacos; Receptor 4 Toll-Like/genética; Receptor 4 Toll-Like/imunologia; Ácido Trinitrobenzenossulfônico/efeitos adversos; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/imunologia

Palavras-chave

Th17 cell; colitis; inflammation; majonoside R2; ocotillol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Linfócitos T Reguladores / Colite / Ginsenosídeos / Células Th17 / Panax Limite: Animals / Humans Idioma: En Revista: J Agric Food Chem Ano de publicação: 2015 Tipo de documento: Article

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