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PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice.
Ghonim, Mohamed A; Pyakurel, Kusma; Ibba, Salome V; Wang, Jeffrey; Rodriguez, Paulo; Al-Khami, Amir A; Lammi, Matthew R; Kim, Hogyoung; Zea, Arnold H; Davis, Christian; Okpechi, Samuel; Wyczechowska, Dorota; Al-Ghareeb, Kamel; Mansy, Moselhy S; Ochoa, Augusto; Naura, Amarjit S; Boulares, A Hamid.
Afiliação
  • Ghonim MA; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A. Microbiology and Immunology Department, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt.
  • Pyakurel K; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Ibba SV; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Wang J; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Rodriguez P; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A. Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Al-Khami AA; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A. Department of Zoology, Faculty of Science, Tanta University, Tanta 31527, Egypt.
  • Lammi MR; Pulmonary and Critical Care Section, School of Medicine, Louisiana State University; New Orleans, LA 70112, U.S.A.
  • Kim H; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Zea AH; Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Davis C; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Okpechi S; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Wyczechowska D; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Al-Ghareeb K; Microbiology and Immunology Department, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt.
  • Mansy MS; Microbiology and Immunology Department, Faculty of Pharmacy, Al-Azhar University, Cairo 11651, Egypt.
  • Ochoa A; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Naura AS; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A.
  • Boulares AH; The Stanley Scott Cancer Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, U.S.A. hboulr@lsuhsc.edu.
Clin Sci (Lond) ; 129(11): 951-62, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26205779

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Asma / Poli(ADP-Ribose) Polimerases / Antiasmáticos / Antialérgicos / Antígenos de Dermatophagoides / Inibidores de Poli(ADP-Ribose) Polimerases / Pulmão Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Egito

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Asma / Poli(ADP-Ribose) Polimerases / Antiasmáticos / Antialérgicos / Antígenos de Dermatophagoides / Inibidores de Poli(ADP-Ribose) Polimerases / Pulmão Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Egito