Alzheimer's in 3D culture: challenges and perspectives.

D'Avanzo, Carla; Aronson, Jenna; Kim, Young Hye; Choi, Se Hoon; Tanzi, Rudolph E; Kim, Doo Yeon

D'Avanzo, Carla; Aronson, Jenna; Kim, Young Hye; Choi, Se Hoon; Tanzi, Rudolph E; Kim, Doo Yeon.

Afiliação

D'Avanzo C; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Aronson J; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Kim YH; Biomedical Omics Group, Korea Basic Science Institute, Cheongju-si, Chungbuk, Republic of Korea.
Choi SH; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Tanzi RE; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.
Kim DY; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

Bioessays ; 37(10): 1139-48, 2015 Oct.

Article em En | MEDLINE | ID: mdl-26252541

Assuntos

Doença de Alzheimer/patologia; Técnicas de Cultura de Células/métodos; Células-Tronco Neurais/patologia; Precursor de Proteína beta-Amiloide/genética; Animais; Modelos Animais de Doenças; Humanos; Camundongos; Células-Tronco Neurais/citologia

Palavras-chave

3D culture; APP; Alzheimer's disease; human stem cell; presenelin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas de Cultura de Células / Células-Tronco Neurais / Doença de Alzheimer Limite: Animals / Humans Idioma: En Revista: Bioessays Assunto da revista: BIOLOGIA / BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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