Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy.

Pan, Chong-Xian; Zhang, Hongyong; Tepper, Clifford G; Lin, Tzu-yin; Davis, Ryan R; Keck, James; Ghosh, Paramita M; Gill, Parkash; Airhart, Susan; Bult, Carol; Gandara, David R; Liu, Edison; de Vere White, Ralph W

Pan, Chong-Xian; Zhang, Hongyong; Tepper, Clifford G; Lin, Tzu-yin; Davis, Ryan R; Keck, James; Ghosh, Paramita M; Gill, Parkash; Airhart, Susan; Bult, Carol; Gandara, David R; Liu, Edison; de Vere White, Ralph W.

Afiliação

Pan CX; Department of Internal Medicine, Division of Hematology/Oncology, University of California Davis, Sacramento, CA, 95817, United States of America; Department of Urology, University of California Davis, Sacramento, CA, 95817, United States of America; VA Northern California Health Care System, Mather
Zhang H; Department of Internal Medicine, Division of Hematology/Oncology, University of California Davis, Sacramento, CA, 95817, United States of America.
Tepper CG; Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, CA, 95817, United States of America.
Lin TY; Department of Internal Medicine, Division of Hematology/Oncology, University of California Davis, Sacramento, CA, 95817, United States of America.
Davis RR; Department of Pathology and Laboratory Medicine, University of California Davis, Sacramento, CA, 95817, United States of America.
Keck J; The Jackson Laboratory, Sacramento, CA, 95838, United States of America.
Ghosh PM; Department of Urology, University of California Davis, Sacramento, CA, 95817, United States of America; VA Northern California Health Care System, Mather, CA, 95655, United States of America; Department of Biochemistry and Molecular Medicine, University of California Davis, Sacramento, CA, 95817, Un
Gill P; University of Southern California, Los Angeles, CA, 90089, United States of America.
Airhart S; The Jackson Laboratory, Sacramento, CA, 95838, United States of America.
Bult C; The Jackson Laboratory, Sacramento, CA, 95838, United States of America.
Gandara DR; Department of Internal Medicine, Division of Hematology/Oncology, University of California Davis, Sacramento, CA, 95817, United States of America.
Liu E; The Jackson Laboratory, Sacramento, CA, 95838, United States of America.
de Vere White RW; Department of Urology, University of California Davis, Sacramento, CA, 95817, United States of America.

PLoS One ; 10(8): e0134346, 2015.

Article em En | MEDLINE | ID: mdl-26270481

Assuntos

Imidazóis/farmacologia; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Piridazinas/farmacologia; Quinazolinas/farmacologia; Quinolinas/farmacologia; Neoplasias da Bexiga Urinária/tratamento farmacológico; Neoplasias da Bexiga Urinária/genética; Animais; Feminino; Xenoenxertos; Humanos; Lapatinib; Sistema de Sinalização das MAP Quinases/genética; Masculino; Camundongos; Camundongos Nus; Proteínas de Neoplasias/antagonistas & inibidores; Proteínas de Neoplasias/genética; Proteínas de Neoplasias/metabolismo; Transplante de Neoplasias; Neoplasias da Bexiga Urinária/metabolismo; Neoplasias da Bexiga Urinária/patologia; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridazinas / Quinazolinas / Quinolinas / Neoplasias da Bexiga Urinária / Sistema de Sinalização das MAP Quinases / Imidazóis Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article

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