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The Trp53 delta proline (Trp53ΔP) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development.
Adams, Cassandra J; Yu, Jennifer S; Mao, Jian-Hua; Jen, Kuang-Yu; Costes, Sylvain V; Wade, Mark; Shoemake, Jocelyn; Aina, Olulanu H; Del Rosario, Reyno; Menchavez, Phuong Thuy; Cardiff, Robert D; Wahl, Geoffrey M; Balmain, Allan.
Afiliação
  • Adams CJ; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
  • Yu JS; Department of Radiation Oncology, Department of Stem Cell Biology, Cleveland Clinic Main Campus, Cleveland, Ohio.
  • Mao JH; Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California.
  • Jen KY; Department of Pathology, University of California San Francisco, San Francisco, California.
  • Costes SV; Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California.
  • Wade M; Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.
  • Shoemake J; Department of Radiation Oncology, Department of Stem Cell Biology, Cleveland Clinic Main Campus, Cleveland, Ohio.
  • Aina OH; Department of Pathology and Laboratory Medicine, University of California Davis, Primate Drive, California.
  • Del Rosario R; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
  • Menchavez PT; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
  • Cardiff RD; Department of Pathology and Laboratory Medicine, University of California Davis, Primate Drive, California.
  • Wahl GM; Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, California.
  • Balmain A; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
Mol Carcinog ; 55(9): 1387-96, 2016 09.
Article em En | MEDLINE | ID: mdl-26310697
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Instabilidade Genômica / Carcinogênese / Neoplasias Induzidas por Radiação Limite: Animals Idioma: En Revista: Mol Carcinog Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Instabilidade Genômica / Carcinogênese / Neoplasias Induzidas por Radiação Limite: Animals Idioma: En Revista: Mol Carcinog Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article