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Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.
Spence, Shaun; Greene, Michelle K; Fay, François; Hams, Emily; Saunders, Sean P; Hamid, Umar; Fitzgerald, Marianne; Beck, Jonathan; Bains, Baljinder K; Smyth, Peter; Themistou, Efrosyni; Small, Donna M; Schmid, Daniela; O'Kane, Cecilia M; Fitzgerald, Denise C; Abdelghany, Sharif M; Johnston, James A; Fallon, Padraic G; Burrows, James F; McAuley, Daniel F; Kissenpfennig, Adrien; Scott, Christopher J.
Afiliação
  • Spence S; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Greene MK; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
  • Fay F; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Hams E; Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland.
  • Saunders SP; Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland.
  • Hamid U; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Fitzgerald M; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Beck J; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Bains BK; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
  • Smyth P; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
  • Themistou E; School of Chemistry and Chemical Engineering, Queen's University Belfast, Belfast BT9 5AG, UK.
  • Small DM; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Schmid D; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
  • O'Kane CM; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Fitzgerald DC; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Abdelghany SM; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Faculty of Pharmacy, University of Jordan, Amman 11942, Jordan.
  • Johnston JA; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK. Inflammation Research, Amgen Inc., Thousand Oaks, CA 91320, USA.
  • Fallon PG; Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland. National Children's Research Centre, Our Lady's Children's Hospital, Dublin 12, Ireland.
  • Burrows JF; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
  • McAuley DF; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Kissenpfennig A; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.
  • Scott CJ; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. c.scott@qub.ac.uk.
Sci Transl Med ; 7(303): 303ra140, 2015 Sep 02.
Article em En | MEDLINE | ID: mdl-26333936
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido N-Acetilneuramínico / Nanopartículas / Lectinas Semelhantes a Imunoglobulina de Ligação ao Ácido Siálico / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido N-Acetilneuramínico / Nanopartículas / Lectinas Semelhantes a Imunoglobulina de Ligação ao Ácido Siálico / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido