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Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.
Peter, B; Winter, G E; Blatt, K; Bennett, K L; Stefanzl, G; Rix, U; Eisenwort, G; Hadzijusufovic, E; Gridling, M; Dutreix, C; Hoermann, G; Schwaab, J; Radia, D; Roesel, J; Manley, P W; Reiter, A; Superti-Furga, G; Valent, P.
Afiliação
  • Peter B; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
  • Winter GE; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
  • Blatt K; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
  • Bennett KL; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
  • Stefanzl G; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
  • Rix U; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
  • Eisenwort G; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
  • Hadzijusufovic E; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
  • Gridling M; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
  • Dutreix C; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
  • Hoermann G; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
  • Schwaab J; Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, Vienna, Austria.
  • Radia D; Novartis Oncology, Basel, Switzerland.
  • Roesel J; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
  • Manley PW; Third Medical Department Mannheim, University of Heidelberg, Mannheim, Germany.
  • Reiter A; Division of Clinical Haematology, Guy's Hospital, London, UK.
  • Superti-Furga G; Novartis Oncology, Basel, Switzerland.
  • Valent P; Novartis Oncology, Basel, Switzerland.
Leukemia ; 30(2): 464-72, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26349526
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mastocitose / Estaurosporina / Inibidores de Proteínas Quinases / Mastócitos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Áustria
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mastocitose / Estaurosporina / Inibidores de Proteínas Quinases / Mastócitos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Áustria