Inside Job: Viruses Transfer cGAMP between Cells.
Cell Host Microbe
; 18(3): 263-5, 2015 Sep 09.
Article
em En
| MEDLINE
| ID: mdl-26355209
ABSTRACT
The DNA sensor, cyclic GMP-AMP synthase (cGAS), is essential for the detection of viral infection. In a recent issue of Science, two studies, Bridgeman et al. (2015) and Gentili et al. (2015), report a novel mechanism for propagating an antiviral signal between cells, based on the transfer of the cGAS enzymatic product, cyclic GMP-AMP (cGAMP), in viral particles.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vacínia
/
Vaccinia virus
/
Vírion
/
Células Dendríticas
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Sistemas do Segundo Mensageiro
/
Infecções por HIV
/
HIV-1
/
Interferon beta
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Muromegalovirus
/
Herpesvirus Humano 1
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Cell Host Microbe
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Suíça