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RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors.
Cheng, Haiying; Zou, Yiyu; Ross, Jeffrey S; Wang, Kai; Liu, Xuewen; Halmos, Balazs; Ali, Siraj M; Liu, Huijie; Verma, Amit; Montagna, Cristina; Chachoua, Abraham; Goel, Sanjay; Schwartz, Edward L; Zhu, Changcheng; Shan, Jidong; Yu, Yiting; Gritsman, Kira; Yelensky, Roman; Lipson, Doron; Otto, Geoff; Hawryluk, Matthew; Stephens, Philip J; Miller, Vincent A; Piperdi, Bilal; Perez-Soler, Roman.
Afiliação
  • Cheng H; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York. hcheng@montefiore.org.
  • Zou Y; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Ross JS; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Wang K; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Liu X; Division of Hematology/Oncology, Herbert Irving Comprehensive Cancer Center, New York Presbyterian Hospital-Columbia University Medical Center, New York, New York. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medici
  • Halmos B; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York. Division of Hematology/Oncology, Herbert Irving Comprehensive Cancer Center, New York Presbyterian Hospital-Columbia University Medical Center,
  • Ali SM; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Liu H; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Verma A; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Montagna C; Departments of Genetics and Pathology, Molecular Cytogenetic Core, Albert Einstein College of Medicine, Bronx, New York.
  • Chachoua A; Division of Medical Oncology, NYU Langone Medical Center, New York, New York.
  • Goel S; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Schwartz EL; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Zhu C; Department of Pathology, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Shan J; Departments of Genetics and Pathology, Molecular Cytogenetic Core, Albert Einstein College of Medicine, Bronx, New York.
  • Yu Y; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Gritsman K; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Yelensky R; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Lipson D; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Otto G; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Hawryluk M; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Stephens PJ; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Miller VA; Foundation Medicine, Inc., Cambridge, Massachusetts.
  • Piperdi B; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
  • Perez-Soler R; Division of Medical Oncology, Department of Medicine, Albert Einstein College of Medicine of Yeshiva University/Montefiore Medical Center, Bronx, New York.
Cancer Discov ; 5(12): 1262-70, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26370156
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Amplificação de Genes / Inibidores de Proteínas Quinases / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Adolescent / Animals / Female / Humans / Male Idioma: En Revista: Cancer Discov Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Amplificação de Genes / Inibidores de Proteínas Quinases / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Adolescent / Animals / Female / Humans / Male Idioma: En Revista: Cancer Discov Ano de publicação: 2015 Tipo de documento: Article