Long-term immunogenicity of single dose of live attenuated hepatitis A vaccine in Indian children.
Indian Pediatr
; 52(8): 687-90, 2015 Aug.
Article
em En
| MEDLINE
| ID: mdl-26388627
ABSTRACT
OBJECTIVES:
To assess immunogenicity of a single dose of live attenuated hepatitis A vaccine in Indian children, ten years after immunization.METHODS:
Of 143 children vaccinated in 2004, 121 children were evaluated in 2014, clinically and for anti-HAV antibodies.RESULTS:
13 children were early vaccine failures who received two doses of HAV vaccine subsequently. 106 (98%) of 108 remaining children had seroprotective levels with a geometric mean titer of 100.5 mIU/mL. On analysis of all 121 children, the immunogenicity was 87.6%.CONCLUSION:
Single dose of live attenuated hepatitis A vaccine provides long-term immunity in Indian children.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vacinas Atenuadas
/
Vacinas contra Hepatite A
/
Anticorpos Anti-Hepatite A
/
Hepatite A
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
/
Infant
País/Região como assunto:
Asia
Idioma:
En
Revista:
Indian Pediatr
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Índia