Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase.

Zhang, Ji; Yan, Yi-Jun; An, Jing; Huang, Sheng-Xiong; Wang, Xiang-Jing; Xiang, Wen-Sheng

Zhang, Ji; Yan, Yi-Jun; An, Jing; Huang, Sheng-Xiong; Wang, Xiang-Jing; Xiang, Wen-Sheng.

Afiliação

Zhang J; School of Life Science, Northeast Agricultural University, No. 59 Mucai Street, Xiangfang District, Harbin, 150030, China. zhangji@neau.edu.cn.
Yan YJ; School of Life Science, Northeast Agricultural University, No. 59 Mucai Street, Xiangfang District, Harbin, 150030, China. quasar110@126.com.
An J; Kunming Institute of Botany, Chinese Academy of Sciences, No. 132 Lanhei Road, Panlong District, Kunming, 650201, China. quasar110@126.com.
Huang SX; School of Life Science, Northeast Agricultural University, No. 59 Mucai Street, Xiangfang District, Harbin, 150030, China. Ajsyz1987@163.com.
Wang XJ; Kunming Institute of Botany, Chinese Academy of Sciences, No. 132 Lanhei Road, Panlong District, Kunming, 650201, China. sxhuang@mail.kib.ac.cn.
Xiang WS; School of Life Science, Northeast Agricultural University, No. 59 Mucai Street, Xiangfang District, Harbin, 150030, China. wangneau2013@163.com.

Microb Cell Fact ; 14: 152, 2015 Sep 24.

Article em En | MEDLINE | ID: mdl-26400541

Assuntos

Regulação Bacteriana da Expressão Gênica/genética; Ivermectina/análogos & derivados; Ivermectina/síntese química; Policetídeo Sintases/metabolismo; Animais; Inseticidas/metabolismo; Ivermectina/metabolismo; Modelos Moleculares

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ivermectina / Regulação Bacteriana da Expressão Gênica / Policetídeo Sintases Limite: Animals Idioma: En Revista: Microb Cell Fact Assunto da revista: BIOTECNOLOGIA / MICROBIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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