The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis.

Denzler, Rémy; Stoffel, Markus

Denzler, Rémy; Stoffel, Markus.

Afiliação

Denzler R; Institute of Molecular Health Sciences, ETH Zurich, Otto-Stern-Weg 7, HPL H36, 8093 Zurich, Switzerland. Electronic address: denzler@biol.ethz.ch.
Stoffel M; Institute of Molecular Health Sciences, ETH Zurich, Otto-Stern-Weg 7, HPL H36, 8093 Zurich, Switzerland. Electronic address: stoffel@biol.ethz.ch.

Mol Cell ; 60(1): 4-6, 2015 Oct 01.

Article em En | MEDLINE | ID: mdl-26431024

ABSTRACT

ABSTRACT

In this issue, Fang and Bartel (2015) report the identification of novel sequence and structural features of human pri-miRNAs, which--together with previously identified sequence motifs--define a unifying model of mammalian pri-miRNAs and advances the de novo design of artificial pri-miRNAs.

Assuntos

Biologia Computacional/métodos; MicroRNAs/metabolismo; Precursores de RNA/química; Humanos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Precursores de RNA / Biologia Computacional / MicroRNAs Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article

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