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Crawling with Virus: Translational Insights from a Neonatal Mouse Model on the Pathogenesis of Respiratory Syncytial Virus in Infants.
You, Dahui; Saravia, Jordy; Siefker, David; Shrestha, Bishwas; Cormier, Stephania A.
Afiliação
  • You D; Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
  • Saravia J; Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
  • Siefker D; Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
  • Shrestha B; Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
  • Cormier SA; Department of Pediatrics, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA Children's Foundation Research Institute at Le Bonheur Children's Hospital, Memphis, Tennessee, USA scormier@uthsc.edu.
J Virol ; 90(1): 2-4, 2016 01 01.
Article em En | MEDLINE | ID: mdl-26446604
The infant immune response to respiratory syncytial virus (RSV) remains incompletely understood. Here we review the use of a neonatal mouse model of RSV infection to mimic severe infection in human infants. We describe numerous age-specific responses, organized by cell type, observed in RSV-infected neonatal mice and draw comparisons (when possible) to human infants.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Sinciciais Respiratórios / Infecções por Vírus Respiratório Sincicial / Modelos Animais de Doenças / Interações Hospedeiro-Patógeno Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: J Virol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Sinciciais Respiratórios / Infecções por Vírus Respiratório Sincicial / Modelos Animais de Doenças / Interações Hospedeiro-Patógeno Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: J Virol Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos