TransgeneOmics--A transgenic platform for protein localization based function exploration.
Methods
; 96: 69-74, 2016 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-26475212
ABSTRACT
The localization of a protein is intrinsically linked to its role in the structural and functional organization of the cell. Advances in transgenic technology have streamlined the use of protein localization as a function discovery tool. Here we review the use of large genomic DNA constructs such as bacterial artificial chromosomes as a transgenic platform for systematic tag-based protein function exploration.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Engenharia Genética
/
DNA Complementar
/
Transgenes
/
Genômica
/
Imagem Molecular
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Methods
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Alemanha