Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.

Li, Shengjian; Liang, Yu-He; Mariano, Jennifer; Metzger, Meredith B; Stringer, Daniel K; Hristova, Ventzislava A; Li, Jess; Randazzo, Paul A; Tsai, Yien Che; Ji, Xinhua; Weissman, Allan M

Li, Shengjian; Liang, Yu-He; Mariano, Jennifer; Metzger, Meredith B; Stringer, Daniel K; Hristova, Ventzislava A; Li, Jess; Randazzo, Paul A; Tsai, Yien Che; Ji, Xinhua; Weissman, Allan M.

Afiliação

Li S; From the Laboratory of Protein Dynamics and Signaling.
Liang YH; Macromolecular Crystallography Laboratory, and.
Mariano J; From the Laboratory of Protein Dynamics and Signaling.
Metzger MB; From the Laboratory of Protein Dynamics and Signaling.
Stringer DK; From the Laboratory of Protein Dynamics and Signaling.
Hristova VA; From the Laboratory of Protein Dynamics and Signaling.
Li J; Structural Biophysics Laboratory, Center for Cancer Research, NCI, National Institutes of Health, Frederick, Maryland 21702 and.
Randazzo PA; the Laboratory of Cell and Molecular Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Maryland 20892.
Tsai YC; From the Laboratory of Protein Dynamics and Signaling.
Ji X; Macromolecular Crystallography Laboratory, and jix@mail.nih.gov.
Weissman AM; From the Laboratory of Protein Dynamics and Signaling, weissmaa@mail.nih.gov.

J Biol Chem ; 290(51): 30225-39, 2015 Dec 18.

Article em En | MEDLINE | ID: mdl-26475854

Assuntos

Enzimas de Conjugação de Ubiquitina/química; Ubiquitina-Proteína Ligases/química; Ubiquitinação; Humanos; Mutação; Ligação Proteica; Estrutura Terciária de Proteína; Enzimas de Conjugação de Ubiquitina/genética; Enzimas de Conjugação de Ubiquitina/metabolismo; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

E3 ubiquitin ligase; RING finger; allosteric regulation; crystallography; proteolysis; ubiquitin; ubiquitin-conjugating enzyme (E2 enzyme)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Enzimas de Conjugação de Ubiquitina / Ubiquitina-Proteína Ligases / Ubiquitinação Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article

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