Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.

Wang, Jiuyu; Li, Jiazhi; Zhao, Hongtu; Sheng, Gang; Wang, Min; Yin, Maolu; Wang, Yanli

Wang, Jiuyu; Li, Jiazhi; Zhao, Hongtu; Sheng, Gang; Wang, Min; Yin, Maolu; Wang, Yanli.

Afiliação

Wang J; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Li J; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhao H; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Sheng G; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang M; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Yin M; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Wang Y; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; Beijing Key Laboratory of Noncoding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: ylwang@ibp.ac.cn.

Cell ; 163(4): 840-53, 2015 Nov 05.

Article em En | MEDLINE | ID: mdl-26478180

Assuntos

Proteínas Associadas a CRISPR/metabolismo; Sistemas CRISPR-Cas; Endodesoxirribonucleases/metabolismo; Endonucleases/metabolismo; Proteínas de Escherichia coli/metabolismo; Escherichia coli/metabolismo; Sequência de Aminoácidos; Proteínas Associadas a CRISPR/química; Cristalografia por Raios X; Endodesoxirribonucleases/química; Escherichia coli/genética; Escherichia coli/imunologia; Proteínas de Escherichia coli/química; Modelos Biológicos; Modelos Moleculares; Dados de Sequência Molecular; Alinhamento de Sequência

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Escherichia coli / Endodesoxirribonucleases / Endonucleases / Escherichia coli / Proteínas Associadas a CRISPR / Sistemas CRISPR-Cas Idioma: En Revista: Cell Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google