The aryl hydrocarbon receptor links integrin signaling to the TGF-ß pathway.

Silginer, M; Burghardt, I; Gramatzki, D; Bunse, L; Leske, H; Rushing, E J; Hao, N; Platten, M; Weller, M; Roth, P

Silginer, M; Burghardt, I; Gramatzki, D; Bunse, L; Leske, H; Rushing, E J; Hao, N; Platten, M; Weller, M; Roth, P.

Afiliação

Silginer M; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Burghardt I; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Gramatzki D; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Bunse L; Department of Neurology, University Hospital Heidelberg, National Center for Tumor Diseases and German Cancer Consortium (DKTK) Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Leske H; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Rushing EJ; Institute of Neuropathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Hao N; School of Biological Sciences, University of Adelaide, Adelaide, Australia.
Platten M; Department of Neurology, University Hospital Heidelberg, National Center for Tumor Diseases and German Cancer Consortium (DKTK) Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Weller M; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Roth P; Laboratory of Molecular Neuro-Oncology, Department of Neurology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Oncogene ; 35(25): 3260-71, 2016 06 23.

Article em En | MEDLINE | ID: mdl-26500056

Assuntos

Neoplasias Encefálicas/metabolismo; Glioblastoma/metabolismo; Integrinas/metabolismo; Receptores de Hidrocarboneto Arílico/metabolismo; Transdução de Sinais; Fator de Crescimento Transformador beta/metabolismo; Animais; Animais Recém-Nascidos; Anticorpos Neutralizantes/farmacologia; Neoplasias Encefálicas/genética; Neoplasias Encefálicas/patologia; Linhagem Celular Tumoral; Células Cultivadas; Glioblastoma/genética; Glioblastoma/patologia; Hepatócitos/efeitos dos fármacos; Hepatócitos/metabolismo; Humanos; Immunoblotting; Imuno-Histoquímica; Integrinas/antagonistas & inibidores; Integrinas/genética; Camundongos Endogâmicos C57BL; Camundongos Knockout; Naftiridinas/farmacologia; Peptídeos Cíclicos/farmacologia; Interferência de RNA; Receptores de Hidrocarboneto Arílico/antagonistas & inibidores; Receptores de Hidrocarboneto Arílico/genética; Reação em Cadeia da Polimerase Via Transcriptase Reversa; Venenos de Serpentes/farmacologia; Sulfonamidas/farmacologia; Fator de Crescimento Transformador beta/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Transdução de Sinais / Integrinas / Fator de Crescimento Transformador beta / Receptores de Hidrocarboneto Arílico / Glioblastoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça

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