Efficient and facile synthesis of novel stable monodeuterium labeled ractopamine.

Su, Feifei; Wu, Fulong; Tang, He; Wang, Zhonghua; Wu, Fanhong

Su, Feifei; Wu, Fulong; Tang, He; Wang, Zhonghua; Wu, Fanhong.

Afiliação

Su F; School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, China.
Wu F; School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, China.
Tang H; School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, China.
Wang Z; School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, China.
Wu F; Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.

J Labelled Comp Radiopharm ; 58(13-14): 479-82, 2015.

Article em En | MEDLINE | ID: mdl-26526706

ABSTRACT

ABSTRACT

A novel synthetic route to stable deuterium labeled ractopamine was disclosed with 6.49% total yield and 97.7% isotopic abundance. Its structure and the isotope-abundance were confirmed according to (1)H-NMR and high-resolution mass spectrometry.

Assuntos

Deutério/química; Fenetilaminas/síntese química; Fenetilaminas/química

Palavras-chave

deuterium labeling; drug standards; ractopamine; ß-adrenergic agonists

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenetilaminas / Deutério Idioma: En Revista: J Labelled Comp Radiopharm Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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