Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice.

Hogan, Thea; Gossel, Graeme; Yates, Andrew J; Seddon, Benedict

Hogan, Thea; Gossel, Graeme; Yates, Andrew J; Seddon, Benedict.

Afiliação

Hogan T; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London NW3 2PF, United Kingdom;
Gossel G; Institute of Infection, Immunity & Inflammation, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom.
Yates AJ; Institute of Infection, Immunity & Inflammation, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom andrew.yates@glasgow.ac.uk benedict.seddon@ucl.ac.uk.
Seddon B; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, Royal Free Hospital, London NW3 2PF, United Kingdom; andrew.yates@glasgow.ac.uk benedict.seddon@ucl.ac.uk.

Proc Natl Acad Sci U S A ; 112(50): E6917-26, 2015 Dec 15.

Article em En | MEDLINE | ID: mdl-26607449

Assuntos

Envelhecimento/imunologia; Linfócitos T CD4-Positivos/imunologia; Linfócitos T CD8-Positivos/imunologia; Linhagem da Célula; Animais; Citometria de Fluxo; Masculino; Modelos Biológicos

Palavras-chave

Ki67; T-cell homeostasis; kinetic heterogeneity; mathematical modeling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Linfócitos T CD4-Positivos / Linfócitos T CD8-Positivos / Linhagem da Célula Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2015 Tipo de documento: Article

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