Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.

Revoredo, Leslie; Wang, Shengjun; Bennett, Eric Paul; Clausen, Henrik; Moremen, Kelley W; Jarvis, Donald L; Ten Hagen, Kelly G; Tabak, Lawrence A; Gerken, Thomas A

Revoredo, Leslie; Wang, Shengjun; Bennett, Eric Paul; Clausen, Henrik; Moremen, Kelley W; Jarvis, Donald L; Ten Hagen, Kelly G; Tabak, Lawrence A; Gerken, Thomas A.

Afiliação

Revoredo L; Department of Chemistry.
Wang S; Copenhagen Center for Glycomics (CCG), Departments of Cellular and Molecular Medicine and Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen N DK-2200, Denmark.
Bennett EP; Copenhagen Center for Glycomics (CCG), Departments of Cellular and Molecular Medicine and Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen N DK-2200, Denmark.
Clausen H; Copenhagen Center for Glycomics (CCG), Departments of Cellular and Molecular Medicine and Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen N DK-2200, Denmark.
Moremen KW; Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602, USA.
Jarvis DL; Department of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA.
Ten Hagen KG; Developmental Glycobiology Section.
Tabak LA; Section on Biological Chemistry, Department of Health and Human Services, NIDCR, National Institutes of Health, Bethesda, MD 20892, USA.
Gerken TA; Department of Chemistry Department of Pediatrics and Biochemistry, Case Western Reserve University, Cleveland, OH 44106, USA txg2@cwru.edu.

Glycobiology ; 26(4): 360-76, 2016 Apr.

Article em En | MEDLINE | ID: mdl-26610890

Assuntos

Glicopeptídeos/química; Lectinas/química; Mucinas/química; Sialiltransferases/química; Sequência de Aminoácidos/genética; Sítios de Ligação; Carboidratos/química; Carboidratos/genética; Domínio Catalítico; Fucose/análogos & derivados; Fucose/química; Glicopeptídeos/biossíntese; Glicopeptídeos/genética; Glicosilação; Humanos; Lectinas/genética; Mucinas/biossíntese; Mucinas/genética; Filogenia; Ligação Proteica; Conformação Proteica; Estrutura Terciária de Proteína; Sialiltransferases/genética; Especificidade por Substrato

Palavras-chave

glycoprotein biosynthesis; glycosyltransferase; lectin; mucin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sialiltransferases / Glicopeptídeos / Lectinas / Mucinas Limite: Humans Idioma: En Revista: Glycobiology Assunto da revista: BIOQUIMICA Ano de publicação: 2016 Tipo de documento: Article

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