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Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation.
Harder, Markus J; Anliker, Markus; Höchsmann, Britta; Simmet, Thomas; Huber-Lang, Markus; Schrezenmeier, Hubert; Ricklin, Daniel; Lambris, John D; Barlow, Paul N; Schmidt, Christoph Q.
Afiliação
  • Harder MJ; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany;
  • Anliker M; Institute of Transfusion Medicine, University of Ulm, 89081 Ulm, Germany; Institute of Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Service Baden-Württemberg - Hessen and University Hospital Ulm, 89081 Ulm, Germany;
  • Höchsmann B; Institute of Transfusion Medicine, University of Ulm, 89081 Ulm, Germany; Institute of Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Service Baden-Württemberg - Hessen and University Hospital Ulm, 89081 Ulm, Germany;
  • Simmet T; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany;
  • Huber-Lang M; Department of Traumatology, Center of Surgery, University of Ulm, 89081 Ulm, Germany;
  • Schrezenmeier H; Institute of Transfusion Medicine, University of Ulm, 89081 Ulm, Germany; Institute of Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Service Baden-Württemberg - Hessen and University Hospital Ulm, 89081 Ulm, Germany;
  • Ricklin D; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19102;
  • Lambris JD; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19102;
  • Barlow PN; School of Chemistry, University of Edinburgh, Edinburgh EH9 3JJ, United Kingdom; and School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JJ, United Kingdom.
  • Schmidt CQ; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, 89081 Ulm, Germany; christoph.schmidt@uni-ulm.de.
J Immunol ; 196(2): 866-76, 2016 Jan 15.
Article em En | MEDLINE | ID: mdl-26643478
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Proteínas Inativadoras do Complemento C3b / Fator H do Complemento / Via Alternativa do Complemento / Inativadores do Complemento Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Immunol Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Proteínas Inativadoras do Complemento C3b / Fator H do Complemento / Via Alternativa do Complemento / Inativadores do Complemento Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Immunol Ano de publicação: 2016 Tipo de documento: Article